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(b) NIR-I and (d) NIR-II Fluorescence intensity in tumor region at various time points (024 h) after i.v

Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)

Accordingly, a short-term DMF treatment of an oligodendrocyte cell line did not prevent a hydrogen peroxide-mediated death, and a DMF treatment in a model of toxic demyelination was not able to prevent demyelination (41)

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The liver performs over 500 vital functions, including the storage and metabolism of essential nutrients

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